Differin Night Cream with Hyaluronic Acid, Restorative Night Moisturizer by the Makers of Differin Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 2.5 oz (Packaging May Vary)
Original price was: $15.83.$14.41Current price is: $14.41.
Price: $15.83 - $14.41
(as of Sep 23, 2025 05:52:07 UTC – Details)
Differin Restorative Night Moisturizer deeply moisturizes skin overnight, visibly improving skin texture for softer, smoother, more radiant looking skin. This dermatologist-developed and -tested moisturizer is formulated with hyaluronic acid which binds to water to help retain natural moisture and keep skin looking plump. Allantoin helps soften and soothe, while ceramides help maintain and restore the skin barrier to lock in moisture for a full 24 hours. The result is a moisturizer that immediately soothes and deeply hydrates dry, flaky skin overnight.
Product Dimensions : 1.69 x 1.89 x 5.32 inches; 0.01 ounces
Item model number : 0299.022049
Department : Beauty & Personal Care
UPC : 302990220490
Manufacturer : Galderma
ASIN : B07SQHD8Z5
Best Sellers Rank: #7,792 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #220 in Face Moisturizers
Customer Reviews: 4.5 4.5 out of 5 stars 8,162 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Hydrating formula with hyaluronic acid, ceramides, and allantoin to visibly improve skin texture by hydrating dry skin overnight
Hyaluronic acid is naturally found in skin and binds to water to help retain natural moisture and keep skin looking plump
Ceramides help maintain and restore the skin barrier to lock in moisture for a full 24 hours
Allantoin soothes dry, flaky skin
Dermatologist developed and tested formula that is non irritating, fragrance free, and non comedogenic
TRAVEL SIZE TOILETRIES: This product is under 3.4 fl oz, making it easy to take with you on your next vacation or trip
Customers say
Customers love this moisturizer for its effectiveness on dry skin and ability to keep it hydrated without feeling greasy. The cream receives positive feedback for its soft, smooth feel, and one customer notes it’s better than Cerave Moisturizing Cream. While some customers say it doesn’t irritate sensitive skin, others report breakouts and stinging sensations.
13 reviews for Differin Night Cream with Hyaluronic Acid, Restorative Night Moisturizer by the Makers of Differin Gel, Gentle Skin Care for Acne Prone Sensitive Skin, 2.5 oz (Packaging May Vary)
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Original price was: $15.83.$14.41Current price is: $14.41.
MalPal –
Great Product
I love the quality of this product, not too greasy, hydrates well, and helps my skin
Billy boone –
Smooth skin
Good stuff..made my skin nice and smooth
TXMom –
Great Nightly Moisturizer
I started pairing Differin Restorative Nightly Moisturizing Cream w/ Differin Gel to use nightly. I was using Differin Gel w/ another nightly moisturizer (sensitive skin) Ive used forever & wasn’t tackling the extreme dryness Differin Gel causes. Since adding the Differin Moisturizer Cream its been 100% better on dryness, redness, and irritation! Took about 2 weeks to actually see improvement (see pics). It says may also purge some new pimples to surface at beginning.Im in my 40’s and have adult cystic acne. Its pretty bad & hormone derived. Used prescription creams & oral meds for many years. My dermatologist recommended I switch to Differin Gel at night & a prescription compound antibiotic cream in morning, along w/ continued Sprinolactone. I ALWAYS use Elta MD tinted sunscreen SPF 44 also to avoid sun irritations as well. I hope after 6 months my cystic areas are no longer resurfacing, but so far Im very pleased w/ this product.If a recurring cyst starts to surface (I have very deep areas that will resurface) it goes away in few days & easy to coverup without pain or redness in that area. My skin is tightening & younger looking w/ less wrinkles as a great plus also!This product is not for all types of acne. So I’d ask a dr if recommended. It used to be Rx only. I highly encourage also pairing w/ the Differin Nightly Moisturizer Cream to reduce the side effects from the Differin gel which is going to occur w/ this product guaranteed! I do not want to use generic accutane which has very high risks to liver & is really all that is left after this regimen per my dermatologist.
MJ –
Meh
I bought this set first. I love the cleanser! The .5 oz 1% Differin didnât last long because I was hesitant to put it on thin when I was just out of the shower. Plus I put it on twice per day for the first week. It killed the little tube fast!The 1% & 2% dark spot both remove acne scars, flat moles, suntan stains & some wrinkles. Iâve been using it on my face, neck, arms & hands. I donât use it every day. It seems to keep working a few days after application. And definitely do put it on ASAP after showering. It spreads a lot thinner & uses a lot less compared to dry skin. Like they say, using more doesnât make a difference. Be very careful when washing. And definitely use the differin gentle cleanser. Exfoliating can make it very painful. Definitely wash at least once per day. Twice if you leave the house. Some days I had a lot of sloughing. Washing twice per day kept me from looking hideous. ðI tried the moisturizer with sunscreen. Itâs good.I only used the nightmare moisturizer a couple times, so far Iâm not a fan. (Separate purchase.)My dermatologist recommended Differin 2%. She said to not use it in summer/sunny weather because it can cause staining. She said to use sunscreen if going out.If I was starting over & not wanting to buy everything to start, Iâd just buy the 2% dark spot remover, (per my dermatologist,) and the gentle cleanser.My skin is getting so smooth & soft that it barely needs moisturizer. It was feeling dry right after I used moisturizer so it is making a huge difference.
Debbie D. –
Amazing
I have only used this for one night, but I am amazed at the results. The cream did not sting and quickly sank into my skin. I woke up to skin that was hydrated, not oily, and the ongoing redness on my cheeks has dramatically gone down. My skin looks happy and healthier. All this from just using this product over just one night. I feel like I have discovered the Holy Grail of nighttime moisturizers. Purchasing the daytime moisturizer now.
Sophie Bertain –
Super gentle and moisturizing
This works so well! I have already used it a lot and will be buying a new one! helps my acne but also keeps my skin moisturized
Vivian Smith –
Nighttime
Good night time moisturizer but need to apply twice to get full effect
Michelle Gipson –
Great Product
Light weight amazing for my skin.
eugenia cristino –
fantastic
Estefania Carrillo –
El producto llegó más rápido que lo estimado, la crema es excelente, me ha ayudado a desaparecer granitos pequeños y controlar mi acné, además deja la piel suave e hidratada, me encanta
Perla –
Ligero pero super hidratante, sin perfume.
Lisa M. –
Early days but so far this is great moisturizer for my face
Mai Le –
Upon using it for about 3 days, I started getting a weird rash/hive on my cheeks and chin as seen in the second pic. At the time I thought it was food allergy, though it was weird as I donât normally get allergic to any food. By night time the rash had subsided somewhat so I went and put this night gel on as usual. By the next morning the rash had severely worsened as seen in the first pic. Then I knew to stop using this gel immediately. It was so itchy I was almost in pain for days, but as soon as I donât put this gel on again it started going down.I donât know what specifically caused the reaction, but suffice to say Iâll never touch this stuff again.